A sound background in dermatopathology is essential for the diagnosis of both inflammatory dermatoses and cutaneous tumors. This book provides an introduction to the principles of dermatopathology, aimed primarily at dermatologists and pathologists in training, but useful for a wide audience Everyone interested in dermatopathology will profit from combined knowledge of 4 experienced dermatopathologists, uniform structure approach concentrating on common diagnoses, logical presentation of clinical and histological features, large clearly labeled illustrations, clues for differential diagnostic considerations. All pictures are in color, printed on high-quality paper, clearly labeled and designed to help every reader become skilled at identifying both patterns and specific diagnostic features rapidly. A dermatopathology designed to be used, not just read – written by practitioners for daily practice.
New biological techniques and a revival of interest in both acute and chronic wound healing have led to an enormously improved understanding of the cellular and chemical complexities of the healing process. Exciting developments in the evolution of epidermal biology are creating new opportunities for research and clinical applications in wound healing. Edited by an expert team of researchers and clinicians, The Epidermis in Wound Healing combines current information with the latest research results to provide a complete picture of the most recent advances in the field. The book focuses on biological advances that improve knowledge and stimulate development in wound therapy. The chapter authors address quantifying repair in the epidermis, biological and clinical elements of wound healing, state-of-the-art approaches to understanding and treating wounds, and gene therapy during wound repair. A discussion on the underlying chemistry of acute and chronic healing describes the special challenges presented by chronic wounds. Featuring the most up-to-date information available, the book chronicles the progress and practices in the field of wound therapy over the past 30 years. This reference will be an essential tool in the generation of innovations and applications in epidermal biology.
Intravenous Immunoglobulins in Dermatology is the first book to bring together the latest developments in this area. With full color throughout, each chapter focuses on clinical differentiation and pathophysiology and provides key laboratory and clinical observations. In addition, there is a brief summary of current treatment options. Some topics include mechanisms of action, chronic urticaria, Kawasaki Disease, blistering disorders, and assessment of intravenous immunoglobulin products.
Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving efficacy, "arming" mAbs, novel alternative Ab constructs, increasing half-lives, alternative concepts employing non-immunoglobulin scaffolds, novel therapeutic approaches, a market analysis of therapeutic mAbs, and future developments in the field. The concepts and technologies are illustrated by examples of recombinant antibodies being used in the clinic or in development. This book will appeal to both newcomers and experienced scientists in the field, biology and biotechnology students, research and development departments in the pharmaceutical industry, medical researchers, clinicians, and biotechnology investors.
The immuno-compromised patient is more susceptible to a broader range of infections than others, and infections of the respiratory tract are among the first and most common to be encountered.
In this book the authors review current options for management for a group of patients that present unique challenges to the clinician, and for whom the choices of effective therapy are often limited.
Most up to date book available dedicated specifically to this topic Major management issue in respiratory medicine for critical care, transplant and cancer patients Reviews important new advances in therapeutics, including drug resistance
Long considered the defining work in Hepatology, this trusted 2-volume masterwork has been refocused to zero in on just the clinical knowledge you need to provide today’s best patient care. The most comprehensive text on the subject, this book is still thoroughly grounded in basic science—but now that science is focused on the most clinically relevant developments. Find definitive coverage of all aspects of liver disease in a new full-color format that keeps pace with your evolving practice.* Covers all liver diseases currently seen in clinical practice—in two clinically focused volumes. * Replaces previous editions’ basic science section with the new, more concise "Pathophysiology of Therapeutic Targets" section. * Highlights key references, all current and up to date, to help you get straight to the significant literature. * Contains new contributions from recognized experts worldwide. * Presents hundreds of detailed illustrations, now in full color!
Clinical Hepatology – Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases.
Clinical Hepatology – Principles and Practice of Hepatobiliary Diseases provides clear and comprehensive coverage of the etiology, mechanisms of disease, diagnosis, and practical management of the entire spectrum of liver and biliary disorders. It also affords an excellent, evidence-based review of the rapidly expanding field of hepatobiliary diseases.
Hepatic fibrosis is the final common pathway for a multitude of liver injuries. Viral-, immune-, or toxin-mediated liver injuries all result in expansion of the extracellular matrix with distortion of hepatic architecture and development of cirrhosis. Originally thought of as a one-way street, hepatic fibrosis now is recognized as a dynamic process with the potential for significant resolution. Authors in this issue address the genetic determinants of fibrosis, oxidant stress, cellular contractility and vasoregulation, as well as relationships between stellate cell activation, progenitor cells and hepatic regeneration. Current and future antifibrotic therapies are also discussed.
Thoroughly revised and updated, the second edition of this pocket-sized handbook provides comprehensive, concise, evidence-based information on the diagnosis and treatment of GI disease. The Little Black Book of Gastroenterology is a convenient resource offering quick access to vital information and makes a great reference for solving pressing problems on the ward or in the clinic.
